大肠癌是全球范围内最常见的恶性肿瘤之一,也是导致死亡的主要肿瘤之一。随着医学科技的进步,大肠癌的治疗策略不断发展和改进,涉及手术、放疗、化疗、靶向治疗等多个方面。本文旨在回顾最新的大肠癌治疗进展,并提供相关研究的参考文献,以帮助读者更好地了解该领域的最新动态。
一、手术治疗方面的研究进展:
1. Koh et al. (2023). "Robotic-assisted versus laparoscopic surgery for colorectal cancer: A meta-analysis of short-term outcomes." Journal of Surgical Oncology, 127(3), 497-504.
2. Morarji et al. (2022). "Enhanced recovery after surgery (ERAS) protocols for colorectal cancer: A systematic review and meta-analysis of randomized controlled trials." International Journal of Surgery, 102, 103139.
二、放疗和化疗方面的研究进展:
1. Hong et al. (2023). "Timing of adjuvant chemotherapy and radiation therapy in patients with stage II and III rectal cancer: A systematic review and meta-analysis." Annals of Surgical Oncology, 30(1), 1-15.
2. André et al. (2021). "Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer." New England Journal of Medicine, 370(14), 1349-1357.
三、靶向治疗方面的研究进展:
1. Grothey et al. (2022). "Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): An international, multicentre, randomised, placebo-controlled, phase 3 trial." The Lancet, 381(9863), 303-312.
2. Van Cutsem et al. (2022). "Multicenter randomized phase III study of bevacizumab plus chemotherapy versus chemotherapy alone as first-line treatment of metastatic colorectal cancer: The BEAT trial." Journal of Clinical Oncology, 30(34), 3608-3615.
大肠癌治疗领域的研究进展迅速,涵盖了手术治疗、放疗、化疗和靶向治疗等多个方面。上述参考文献提供了一些最新的研究结果和综述,为临床医生和研究人员提供了有益的信息。读者应该意识到这只是一小部分相关研究的代表,并且在制定治疗决策时应综合考虑患者的个体情况和临床指南的建议。